The 32-year-old actress - who lost her mother Marcheline Bertrand to ovarian cancer earlier this year - has pledged her time and support to TV star Fran Drescher's Cancer Schmancer Movement.
The charity strives to ensure all women's cancers are diagnosed in Stage 1, when they are most curable.
Fran, 49, told TV show 'Access Hollywood': "Angelina's mother had ovarian cancer and did not win her battle, so she is going to lock elbows with me and we are going to do some things together.
"We are dedicated to ensure that all women's cancers get diagnosed in Stage 1 by galvanising and educating, then we can change policy by signing petitions."